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Infratemporal fossa

The infratemporal fossa (Latin: fossa infratemporalis) is an irregularly shaped space on the side of the skull below the zygomatic arch and deep to the ramus of the mandible. The infratemporal fossa is located below the temporal fossa and is continuous with it.


Borders of infratemporal fossa

The borders or walls of the infratemporal fossa are formed by bones and soft tissue structures, and they are as follows:

  • Superior (roof): greater wing of the sphenoid;
  • Inferior (floor): medial pterygoid muscle;
  • Lateral: medial surface of ramus of the mandible;
  • Medial: lateral pterygoid plate of the pterygoid process (of the sphenoid);
  • Posterior: carotid sheath.
Skull, infratemporal fossa with borders marked in red
Infratemporal fossa by


Contents of infratemporal fossa

The infratemporal fossa serves as a passageway for neurovascular structures that travel between the cranial cavity, temporal fossa and pterygopalatine fossa. It also contains several muscles of mastication. The structures found in the infratemporal fossa are as follows:


Openings of infratemporal fossa

There are several openings in the walls of the infratemporal fossa that connect it with different cavities and fossae of the skull. These openings transmit nerves and blood vessels. The openings of the infratemporal fossa include the following:

  • Foramen ovale
  • Foramen spinosum
  • Petrotympanic fissure
  • Pterygomaxillary fissure

The foramen ovale connects the infratemporal fossa with the middle cranial fossa. It transmits the mandibular nerve (CN V3), lesser petrosal nerve, the accessory meningeal branch of the maxillary artery, and an emissary vein.

The foramen spinosum also connects the infratemporal fossa with the middle cranial fossa of the internal cranial base. This opening serves as a passage for the meningeal branch of the mandibular nerve (CN V3), as well as the middle meningeal artery and vein.

The petrotympanic fissure is located on the temporal bone and serves as a passage for the chorda tympani (a branch of the facial nerve, CN VII) between the tympanic cavity and the infratemporal fossa.

The pterygomaxillary fissure connects the infratemporal fossa with the pterygopalatine fossa and transmits the terminal part of the maxillary artery, as well as the superior alveolar nerve, which is a branch of the maxillary nerve (CN V2).